Van de Ven Double Ends The Toffees' Unbeaten Streak at Brand New Home Ground
Micky van de Ven emerged as the initial backline player to score two goals in a Premier League game for Spurs since Jan Vertonghen in March 2013.
At a glance
The Spurs defender heads into the net two times in opening period
Everton's defender has equalizer disallowed after VAR review
Pape Matar Sarr scores final goal in 89th minute
This loss is the Merseyside club's first at Hill Dickinson Stadium
Micky van de Ven found the net twice as Spurs prolonged their unbeaten run in away games in the top division and handed the Toffees their first defeat at their new home.
Everton were undefeated in their last five matches at their new ground at Bramley-Moore Dock, having left Goodison Park behind after 133 years at the conclusion of last season.
But Tottenham's leader the Dutchman pounced twice from set-pieces in the first half to place their impressive record at risk, and they were unable to turn it around before Pape Matar Sarr - set up by former Toffees attacker the Brazilian - headed home a final goal to put the game to bed.
Jake O'Brien thought he had equalized the tally five minutes after the defender's opener, directing a bullet header past the Spurs keeper from an set-piece.
Beto, meanwhile, failed to convert a number of chances, while the Italian goalkeeper made a series of excellent stops to guarantee Tottenham went five matches on the road unbeaten in the Premier League.
But the video assistant referee intervened, advising the match official to check the goal on the pitchside monitor and the referee ruled that the winger and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
The win elevates the manager's side into third place in the Premier League, a handful of points off local foes and table-toppers Arsenal.
Everton stay in 14th position and are six points clear of the drop zone.
Spurs breakdown: Van de Ven fulfils duties at each end of pitch
Following a drab midweek display in the Champions League against the French side, where they managed a mere attempts on goal, Frank opted for Randal Kolo Muani up front instead of former Toffees player Richarlison.
The new arrival was failed to make much of an impact before being replaced for the substitute after 60 minutes on the pitch, but it emerged he proved unnecessary in the end.
Centre-back the Dutchman transformed into an offensive threat to be reckoned with.
Tottenham's first goal came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball toward the face of goal for an free the defender to head home.
And Ven de Ven - filling in as skipper in the Argentine's absence - notched his next goal in first-half stoppage time as he rose above the England keeper to nod in.
Van de Ven was just as impressive in defence, partnering well with his defensive colleague as the duo handled superbly with the numerous deliveries sent their way by Everton.
Everton analysis: Everton missing finishing touch
The club's new home had been a fortress, but it seems the freshness may have faded slightly and supporters headed to the exits after Sarr's final goal for Spurs.
The break in Everton's unbeaten home run won't be a massive concern for the manager, but their striker situation will be.
Beto and Thierno Barry - the Everton's pair of recognised centre-forwards - had scored just a single goal combined before Sunday's match.
And they were unable to contribute to that poor tally on a damp and dreary night on in Liverpool.
The striker's performance was summed up when he chose to overhead kick a golden opportunity from near the goal, despite having room and time to readjust for a more conventional attempt that would have tested the keeper.
The substitute, as well, was unable to make an impact after coming on for the starter in the second half.
It was not for a shortage of opportunity. The majority of Everton's attacks came through the winger and Ndiaye, who tirelessly whipped threatening balls into the Spurs box.
What next for these two sides?
Everton: The team head to Sunderland in the top flight on early November at 20:00 GMT.
Tottenham: Spurs go to St James' Park on late October for their fourth-round League Cup match against Newcastle.